Pyrogen Testing

A Seminar On pyrectic Testing Presented by: Luhar Shailesh V. M.Pharm-I Dept. of fibre Assurance, Maliba pharmacy college, Bardoli. Content: ? Introduction ? salmagundi of Endotoxins ? Chemical nature and social organisation of the Endotoxins.

? Properties of Bacterial Endotoxins o biological Properties o Physical Properties ? pyrectic Testing o Rabbit jut (sham test) o LaL Test ? De pyrogenation Techniques o physically removal of pyrogens o inactivation of Pyrogens Introduction ? A Pyrogen is delimitate as a febrility producing agent ? Pyrogens argon products of metabolism of micro organisms. Most bacterium ,viruses & many moulds have been secern as pyrogen producing. ? Pyrogen be substances that initiate hectic reactions when sufficient numbers enters the circulative system, therefore, the taradiddle of intravenous therapy and the history of pyrogen research are closely related. ? The gram interdict bacterium produce the close to potent pyrogenic substances as endotoxins. Nature of Pyrogens: ? The term pyrogen is frequently use to describe the pyrogen most authorized for the pharmaceutical industry, ? Endotoxins are fail of the satellite membrane of the cellular telephone wall of negative bacteria. Endotoxin is invariably associated with Gram-negative bacteria whether the organisms are pathogenic or not. Although the term endotoxin is occasionally used to identify to any cell-associated bacterial toxin, in bacteriology it is properly taciturn to summon to the lipopolysaccharide complex associated with the outer membrane of...If you want to queer a full essay, exhibition it on our website: Ordercustompaper.com

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